3 Pack of Thorne Berberine 500 60 Veggie Capsules (3 Bottles)


In stock

3 Pack of Thorne Berberine 500 60 Veggie Capsules (3 Bottles)


SKU: WB-OHB-10-3 Category: Tags: , ,

✔ 100% Money Back Guarantee
✔ Secure Payment Process


Please call 877.572.3444 for Ordering Information!

For Blood Sugar Control

For Triglycerides Control

For metabolic syndrome: blood sugar and triglycerides control

Product Information

Berberine is an alkaloid that is present in a number of plants, including:

Berberis vulgaris (barberry),
Berberis aristata
(tree turmeric),
Berberis aquifolium (Oregon grape),
Hydrastis canadensis
(goldenseal), and
Coptis chinensis

This important plant extract demonstrates important benefits for glucose metabolism, maintenance of healthy lipid levels, insulin sensitivity, cardiac support, weight management, gastrointestinal health, immune modulation, and cognitive support.*


Two Capsules Contain: Berberine HCl (from Indian Barberry extract) (root) (Berberis aristata)    1 g
Other Ingredients: Hypromellose (derived from cellulose) capsule, Microcrystalline Cellulose, Silicon Dioxide, Leucine.
Berberis Concentrate Berberine HCl 85%.
Suggested Use: Take 1-2 capsules two times daily or as recommended by your health-care practitioner.
Servings Per Container: 30
From www.Examine.com (http://examine.com/supplements/Berberine/)

Berberine is an alkaloid that has been isolated from various anti-diabetic plants used in Traditional Chinese Medicine. When tested in isolation, it appears to be causative of many of the benefits associated with the plant. Berberine has various mechanisms of action, but tends to be known as an AMPK activator; alongside AMPK activation, berberine also exerts anti-inflammatory effects, benefits to intestinal health and integrity, possible synergism with anti-depressant medications, lipid and cholesterol lowering effects, andstrong anti-diabetic effects.

The anti-diabetic effects of berberine are the most well-researched, and are partly due to AMPK activation; PTP1B inhibition, which reduces glucose production in the liver, may also contribute, as well as berberine’s anti-inflammatory effects. Comparative research in both animals and humans (as well as one meta-analysis on humans) demonstrate that the anti-diabetic effects of 1500mg of Berberine taken in three doses of 500mg appear to be equal to those of 1500mg Metformin or 4mg Glibenclamide in terms of reducing biomarkers of type 2 diabetes. Berberine is one of the few compounds in Examine’s database to have human evidence to establish it to be as effective as pharmaceuticals.

Berberine is also sometimes recommended for diabetes prevention and therapy, as it does not appear to cause increased body fat as a side effect (associated with Glibenclamide) and may actually reduce body fat. It may also be preferred due to being seen as a “natural” therapeutic option for persons who choose not to use pharmaceuticals (fallacious thinking, but still a topic that needs to be addressed).

Additionally, due to the mechanism of action being AMPK activation, berberine exhibits fairly potent lipid-lowering effects (similar to Metformin), and via other unrelated mechanisms also reduces circulating cholesterol levels; these side effects make berberine desirable for reducing the risk of cardiac complications associated with diabetes.

There are also some less-proven but promising effects associated with berberine supplementation that may protect against diabetic cardiomyopathy and diabetic nephropathy.

Berberine, in short, is an effective anti-diabetes agent that also extends its benefits to persons who do not have diabetes but may have an excess of body fat and rising glucose, triglyceride, or cholesterol levels. Current evidence suggests that it is side-effect free aside from gastrointestinal distress if too much is taken at once, and comparable in potency to two commonly used pharmaceuticals in diabetes treatment (Metformin mostly, with some evidence suggesting comparability to Glibenclamide).

Berberine has many other mechanisms of action that are of interest but are less studied at the moment. At very low doses (1.6mg/kg equivalent to humans, but currently untested) it appears to augment the efficacy of many anti-depressants, possibly by a novel receptor class known as sigma receptors (which are actually the molecular target of the hallucinogen DMT, but berberine is unlikely to cause any trips). It is neuroprotective if taken prior to neurological stressors (although some evidence suggests it should not be used in a rehabilitative manner).

It can enhance glucose and lipid uptake into fat cells while simultaneously suppressing their proliferation, which exerts theoretically powerful anti-obesity effects; currently only two studies have reported fat mass changes over time with berberine, and the amount of fat loss seen over 12 weeks with 1500mg Berberine ranged from 3.6-13% of total body weight. It does appear to work in humans, but the magnitude of benefit is not yet ascertained. Additionally, it might attenuate some fat-burning effects despite these anti-obesity effects, although this has not yet been demonstrated in a living model (berberine may attenuate the rate of weight gain without conferring much inherent weight-loss benefit).

Berberine can also reverse insulin resistance on muscle cells and promote both glucose and lipid uptake into the muscle cells. Unfortunately, the mechanism of action that mediates this (AMPK activation) also appears to suppress muscle growth and may actually reduce muscle mass according to one rodent study. Genetically ablating one protein (atrogin-1) reverses this suppression of muscle growth, and thus berberine has potential to be a potent body recomposition agent, pending future research. The interactions with exercise are unknown, but it is theoretically possible that resistance training or contracting muscle tissues can attenuate or reverse these losses.

Statements and Warnings:

ALLERGY WARNING:  This product is contraindicated in an individual with a history of hypersensitivity to any of its ingredients.
PURITY:  This product does not contain wheat, gluten, corn, yeast, soy, egg, dairy products, or artificial colors, artificial sweeteners, or artificial flavors. This product also does not contain lactose, palmitic acid, magnesium stearate, or stearic acid.

PREGNANCY WARNING:  If pregnant, nursing, or trying to conceive, do not use this product.

INTERACTIONS:  Has been shown to decrease the activity of the cytochrome p450 (CYP) enzymes CYP2D6, CYP2C9, and CYP3A4.

Article on Berberine

1 review for 3 Pack of Thorne Berberine 500 60 Veggie Capsules (3 Bottles)

  1. Garey Simmons

    Absolutely helps reduce my triglycerides.

Add a review

FDA Disclaimer: The products on this site have not been evaluated by the United States Food and Drug Administration and are not intended to diagnose, treat, cure or prevent any disease. It's good to know that our facilities adhere to GMP standards which includes annual inspections by the FDA compliance unit.

Table of Contents:

Shipping and Returns Policy
  • bigstock-delivering-package-4158352Shipping: United States Postal Service Options start at $5.95 any where in the continental United States. Orders over $150, shipping is free domestically. International orders may ship for as low as $15 but further charges may apply due to weight restrictions. UPS or Fedex are available on request and billed at published rates. Our service supplies a tracking number by email once your package ships.
  • Returns: Unopened products may be returned for a refund within 4 weeks of receipt for any reason. We may not accept open bottles due to cGMP regulations. Logged into your account and click on the order in questions and instructions will be given. Further questions may be submitted to Service@OHB3.com or by calling 443-450-4413 or by calling 877-572-3444 and leaving a message for Customer Care.

Why Choose Optimal Health Bridge: (From Stan, Military Pilot Retired, 1st Gulf War.) "If you haven't learned about the numerous benefits to adding supplemental Omega 3 to your diet, I'd encourage you to check out what you are missing. I know every product description tries to convince you that it will greatly improve your life, so I understand your skepticism. I can tell you from personal experience that HIGH QUALITY Omega 3 supplements really HAVE made a SUBSTANTIAL difference in the health of my family and friends. It's not an instantaneous transformation. Give it 4-6 weeks for a fair assessment. However, while it's true I'd like everyone to consider using Omega 3 supplements in their diet, I'm really writing this review to those who already use the product and are looking for a good source. YOU FOUND IT at Optimal Health Bridge. I used Res-Q 1250 for years, and made purchases during their specials to keep the price as low as possible.
Why Advantage Shipping: TRUE OMEGA 3 is virtually the same capsule as Res-Q with a price tag much easier to absorb. If you'll look at the contents you'll see the similarity for yourself in the actual dosage of DHA and EPA. If you go onto OHB's Advantage shipping program (which I highly recommend) the price is the lowest you'll find ANYWHERE and the shipping is free, paid for by the company to encourage your continued use of the Advantage shipping program. This helps to keep everyone's costs low, allows to easy modifications and you never run out of needed nutritional supplements. Once you order from these people you'll begin to understand why I'm willing to provide such an enthusiastic testimonial to their product and to their company. They provide the friendliness and assistance that you might get from a local store, but they keep their margins razor thin. I appreciate local business and support them when I can, but this is one time where I can get all the benefits of using a local business and save well over $1000 annually in supplement costs. If all this seems too good to be true, call the company and ask to speak with Garey, the owner. You'll be transferred to him or he will return your call within a day (barring unusual situations.)
I have admittedly come to think of Garey as a friend, which is the first time an internet supplier has become one of my personal friends.
You'll get the same attention if you'll call him with any questions or concerns. You'll find he believes his business is not merely a way to support his family; rather he is on a "mission" to spread the word about the huge benefits of Omega 3 in fighting heart disease among other ailments. He has other supplements as well, but he limits his inventory to proven, useful supplements. You won't find him promoting fad products or cheap imitations. He created his own brand so he could control with precision the quality of his True Omega. These people and this product will NOT disappoint you. Give yourself a fighting chance against heart disease and other inflammatory issues by trying the product for 4-6 weeks. Talk to Garey about the dosage you should be taking since it really depends on your personal situation and health.

Advantage Shipping Simplicity is Better Than the Res-Q Platinum Program

  • It's free. No annual charge.
  • No set up fee.
  • Easy User Control on Your Profile Page.
  • Free Shipping.
  • Least Expensive Pricing
Call Now ButtonCall Us for Assistance